Softening the impact of having been jilted

If you have recently been jilted or otherwise had a close relationship severed, you are undoubtedly feeling the loss and perhaps even a wee bit of rage (Which actually serves a purpose insofar as it helps one purge the other from one’s life). Your brain is actually going through withdrawal involving the selfsame neurochemical players and brain centers that are involved in reward and addiction. In a nutshell, your dopamine levels are plummeting (sets off cravings), the mood modulator serotonin has taken a nose dive (Blue Funk time), stress hormones are up and there may even be withdrawal symptoms associated with opioid compounds you  produced (and augmented via behavior & diet) which you body is now clamoring for.  The passage of time in concert with physical activity will help take the punch out of this biochemical maelstrom    (More on this can be found in chapter 8 of Anatomy of Love: A Natural History of Mating, Marriage, and Why We Stray )

Here are a few non-pharmaceutical measures that may help:

To help raise dopamine levels in the brain:

 Muncuna (Mucuna pruriens) products such as

 Diet: Eat prepared Fava beans (A legume)

 To help raise serotonin levels in the brain:

 5-hydroxytryptamine (5-HTP)

 Diet: Eat lots of turkey (Tryptophan source – precursor used to generate serotonin)

Take with pyridoxal-5 phosphate – 10 mgs. (A form of B6)

To help modulate stress hormones:

 Standardized Ginseng Extract (Panax ginseng)

 To help curtail endogenous opioids (Compounds generated in one’s body that influence reward and addiction):

Follow the Paleodiet (Fava beans excepted)

 Ask your doctor about putting you on low dose Naltrexone


S-Adenosylmethionine (“SAMe”)


 N-acetyl-Tyrosine, DL-Phenylalanine (Folks with PKU or hypertension should avoid DL-Phenylalanine)


Manyam BV, Dhanasekaran M, Hare TA, ‘Neuroprotective effects of the antiparkinson drug Mucuna pruriens’, Phytother Res. 2004 Sep;18(9):706-12 

Apaydin H, Ertan S, Ozekmekci S, ‘Broad bean (Vicia faba)–a natural source of L-dopa–prolongs “on” periods in patients with Parkinson’s disease who have “on-off” fluctuations’, Mov Disord. 2000 Jan;15(1):164-6

Kaneko H, Nakanishi K, ‘Proof of the mysterious efficacy of ginseng: basic and clinical trials: clinical effects of medical ginseng, korean red ginseng: specifically, its anti-stress action for prevention of disease,’ J Pharmacol Sci. 2004 Jun;95(2):158-62.

Kim DH, Jung JS, Suh HW, Huh SO, Min SK, Son BK, Park JH, Kim ND, Kim YH, Song DK,’ Inhibition of stress-induced plasma corticosterone levels by ginsenosides in mice: involvement of nitric oxide,’ Neuroreport. 1998 Jul 13;9(10):2261-4.

Zioudrou C, Streaty RA, Klee WA, ‘Opioid peptides derived from food proteins. The exorphins,’ J Biol Chem. 1979 Apr 10;254(7):2446-9.

Fukudome S, Yoshikawa M., ‘Opioid peptides derived from wheat gluten: their isolation and characterization,’ FEBS Lett. 1992 Jan 13;296(1):107-11

‘Neuroendocrine effects of SAMe, a novel putative antidepressant,’ J Psychiatr Res, 1990, 24:2.

De Vanna M, Rigamonti R, ‘Oral SAMe in depression’, Curr Ther Res 1992, 52: 478-485.


About Dr. Anthony G. Payne

Most of the time you will find me spinning ideas and web content for client firms and especially physicians (MDs and DOs). Among my many passions are helping others help others, word weaving (Published writer & author, ghostwriter, copywriter, proofreader, editor), and art (Mainly sketching. I revel in Jackson Pollock's art and thus enjoy experimenting with his approach combined with those of other artists). Nature is a focus too, reflected in the fact I have been involved in the deep ecology movement since the 1980s and (more recently) the Forest Church movement. I am also a Celtic Christian monk (Novice monk in 2015, full monk in 2017). This is the realization of a calling I have "flirted with" for many moons now. You are encouraged to check out my "Summer Cloud's Spiritual Watering Hole"​ website to learn more:

Posted on May 23, 2009, in Psychology and tagged , , , , , , , , , , . Bookmark the permalink. Comments Off on Softening the impact of having been jilted.

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